Spontaneous Healing Capacity of Calvarial Bone Defects in mdx Mice
نویسندگان
چکیده
منابع مشابه
Enhanced Calvarial Bone Healing in CD11c-TLR4−/− and MyD88−/− Mice
BACKGROUND Inflammation is integral to the injury response. The inflammatory response is essential to the host defense against infection and also to tissue regeneration and repair. Toll-like receptors (TLRs) are critical activators of the innate immune response and present attractive therapeutic targets for inflammation-modulated tissue regeneration. The authors' previous study showed that depl...
متن کاملSpontaneous healing capacity of rabbit cranial defects of various sizes
PURPOSE This study evaluated the spontaneous healing capacity of surgically produced cranial defects in rabbits with different healing periods in order to determine the critical size defect (CSD) of the rabbit cranium. METHODS Thirty-two New Zealand white rabbits were used in this study. Defects of three sizes (6, 8, and 11 mm) were created in each of 16 randomly selected rabbits, and 15-mm d...
متن کاملEvaluation of bioactive glass and platelet-rich plasma for bone healing in rabbit calvarial defects.
Bone regeneration is an important objective in clinical dental practice and has been used for different applications. The aim of this study was to evaluate the effectiveness of platelet-rich plasma (PRP) and bioactive glass (BG) for bone healing of surgical calvarial defects in rabbits. Two 8-mm defects were prepared in the parietal bones of ten animals, and the animals were randomly assigned t...
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Host blood circulating stem cells are an important cell source that participates in the repair of damaged tissues. The clinical challenge is how to improve the recruitment of circulating stem cells into the local wound area and enhance tissue regeneration. Stromal-derived factor-1 (SDF-1) has been shown to be a potent chemoattractant of blood circulating stem cells into the local wound microenv...
متن کاملInjectable reactive biocomposites for bone healing in critical-size rabbit calvarial defects.
Craniofacial injuries can result from trauma, tumor ablation, or infection and may require multiple surgical revisions. To address the challenges associated with treating craniofacial bone defects, an ideal material should have the ability to fit complex defects (i.e. be conformable), provide temporary protection to the brain until the bone heals, and enhance tissue regeneration with the delive...
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ژورنال
عنوان ژورنال: The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
سال: 2012
ISSN: 1932-8486
DOI: 10.1002/ar.22412